10. Zachary and Margaret Taylor
The couple were married in 1810 and had 6 children together. Perhaps most notably, their daughter Sarah Knox Taylor married Jefferson Davis in 1835. As Zachary’s political rise began, Margaret literally prayed for his defeat, fearing the consequences of his becoming President. Once Zachary had won the Presidency, multiple child births and other life rigors had taken their toll on Margaret, and she remained secluded on the second floor of the White House.